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<p>This work reports the characterization of Ti6Al4V-hydroxyapatite (Ti64-HA) composite fabricated using the direct metal laser sintering (DMLS) technique due to the higher accuracy and better surface quality than the other AM techniques. Ti64-HA composite has gained wide attention due to its low density and higher bioactivity, making it suitable for orthopedic implant applications. However, till now, no one has reported the mechanical, tribological, corrosion, and cell viability properties of DMLS-produced Ti64-HA composites. In the present study, three different compositions (0%, 5%, and 10% HA) were fabricated to evaluate the effect of HA concentration. Along with characterizations related to mechanical and biomedical properties, corrosion behavior was also evaluated in two different bio-media/environments, viz., physiological saline solution (PSS) and simulated body fluid (SBF), to check the in vitro degradation rate. The cell viability of all three samples was checked with the osteoblast cell line (MG63). The highest cell viability was obtained in the case of Ti64-10HA composite, and the lowest was observed for Ti64 alloy. Apart from enhancement in biomedical properties, the addition of HA also lowered the Young’s modulus of elasticity and brought it close to typical human bone, which is a favorable attribute for avoiding stress shielding. Thus, in terms of mechanical properties, biocompatibility, and corrosion behavior, the Ti64-10HA composite was found to be better than the Ti64-5HA composite and the Ti64 alloy.</p>

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Mechanical and biocompatibility assessment of direct metal laser sintering produced Ti6Al4V–hydroxyapatite composite for orthopedic implant application

  • 期刊论文

  • 发表日期：

    2026年3月20日

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  • Vipin Goyal,
  • Shanmuga S. Rathnam,
  • Girish Verma,
  • Uday Shanker Dixit

摘要

This work reports the characterization of Ti6Al4V-hydroxyapatite (Ti64-HA) composite fabricated using the direct metal laser sintering (DMLS) technique due to the higher accuracy and better surface quality than the other AM techniques. Ti64-HA composite has gained wide attention due to its low density and higher bioactivity, making it suitable for orthopedic implant applications. However, till now, no one has reported the mechanical, tribological, corrosion, and cell viability properties of DMLS-produced Ti64-HA composites. In the present study, three different compositions (0%, 5%, and 10% HA) were fabricated to evaluate the effect of HA concentration. Along with characterizations related to mechanical and biomedical properties, corrosion behavior was also evaluated in two different bio-media/environments, viz., physiological saline solution (PSS) and simulated body fluid (SBF), to check the in vitro degradation rate. The cell viability of all three samples was checked with the osteoblast cell line (MG63). The highest cell viability was obtained in the case of Ti64-10HA composite, and the lowest was observed for Ti64 alloy. Apart from enhancement in biomedical properties, the addition of HA also lowered the Young’s modulus of elasticity and brought it close to typical human bone, which is a favorable attribute for avoiding stress shielding. Thus, in terms of mechanical properties, biocompatibility, and corrosion behavior, the Ti64-10HA composite was found to be better than the Ti64-5HA composite and the Ti64 alloy.