<p>Vertical centrifugal casting process is used for producing pipes, tubes, or shapes connected to a pipe. This casting process is very complex and requires a lot of knowledge and skills. In order to obtain a reliable casting process, a laboratory prototype of a fully automated machine for vertical centrifugal casting in vacuum was developed in collaboration with FRIPOL Ltd., a company from Ljubešćica, Croatia. Casting a stainless steel EN 1.4301 tube with an outer diameter of 84 mm, a height of 42 mm and thickness of 7 mm was first simulated. Subsequently, the effect of process parameters on microstructure was determined on experimental casted tubes. After visual control, a metallographic analysis was made, and the hardness of the casting was tested. Chemical composition was also determined. Simulation results showed shrinkage porosity on inner side of the casting, at the place of last solidification, which was also confirmed with experimental results. This can be reduced by choosing correct casting parameters but cannot be avoided. Coated graphite crucible and hybrid graphite/SiC crucible caused carburization of the molten metal during melting and an increased appearance of carbides in the microstructure, which could lower the corrosion resistance of the casting. Carburisation did not occur with the use of ceramic Al₂O₃ crucible.</p>