Scholarlink

<p>Placental site trophoblastic tumour (PSTT) is a rare subtype of gestational trophoblastic neoplasm arising from placental implantation site. It often presents with atypical clinical features and is resistant to chemotherapy. Rarely, it may lead to formation of arterio-venous malformation (AVM) due to vascular invasion by proliferating intermediate trophoblasts. Here, we present a rare case of PSTT, initially managed with subtotal hysterectomy and subsequently developed a large pelvic AVM. She had life-threatening haemorrhage and was treated by surgical resection after failed endovascular embolization. Currently, the patient remains in complete remission at 18 months follow-up. Only three reports of AVM associated with PSTT have been documented so far. To the best of our knowledge, this is the fourth such case reported in the literature.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Navigating Arterio-venous Malformations in Placental Site Trophoblastic Tumour: Dilemmas and Successful Management

  • 期刊论文

  • 发表日期：

    2026年1月5日

查看全文
  • Swati Tomar,
  • Suvidya Singh,
  • Sandeep R. Mathur,
  • M. D. Ray,
  • Sachin Khurana,
  • Neena Malhotra,
  • Seema Singhal

摘要

Placental site trophoblastic tumour (PSTT) is a rare subtype of gestational trophoblastic neoplasm arising from placental implantation site. It often presents with atypical clinical features and is resistant to chemotherapy. Rarely, it may lead to formation of arterio-venous malformation (AVM) due to vascular invasion by proliferating intermediate trophoblasts. Here, we present a rare case of PSTT, initially managed with subtotal hysterectomy and subsequently developed a large pelvic AVM. She had life-threatening haemorrhage and was treated by surgical resection after failed endovascular embolization. Currently, the patient remains in complete remission at 18 months follow-up. Only three reports of AVM associated with PSTT have been documented so far. To the best of our knowledge, this is the fourth such case reported in the literature.