Purpose <p>The present study was conducted to estimate the incidence of intraoperative and postoperative adverse events in patients undergoing surgery for gynecologic malignancies.</p> Methods <p>Preoperative patient characteristics, surgical procedure and disease characteristics were studied for a cohort of patients undergoing surgical management for gynecologic malignancies at AIIMS Rishikesh from 2021 to 2023. The incidence of adverse events and complications was analyzed intraoperatively and postoperatively at seven, fourteen and thirty and graded according to Common Terminological Criteria for Adverse Events 5.0.</p> Results <p>The preoperative evaluation was done among 124 patients, out of which 10 were lost to follow-up. One hundred and fourteen patients were finally analyzed. The most common intraoperative adverse event was hemorrhage that led to blood transfusion 29/114 (25.45%), followed by bowel injury 9/114 (7.89%). The most common postoperative complication was also blood transfusion 29/114 (25.45%) followed by wound infection 25/114 (21.93%). The significant independent risk factors associated with adverse events were the patient’s serum albumin and ECOG performance scores more than two. Increased blood loss, ASA grade more than 2 and intermediate surgical complexity score further increased the odds of occurrence of adverse events.</p> Conclusion <p>The provision of satisfactory preoperative care and optimization for surgery is a critical step in reducing adverse events and improving patient safety and quality of life in women with gynecologic cancer who are undergoing radical operative procedures. It is necessary to do additional research to identify areas of decreased compliance with guidelines for initiatives to improve adherence to evidence-based medicine practices to be developed.</p>

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Adverse Events: An Intrinsic Aspect of Gynecologic Oncological Surgery—A Single-Center Experience

  • Smrati Sabnani,
  • Amrita Gaurav,
  • Shriya Rawat,
  • Kavita Khoiwal,
  • Om Kumari,
  • Ipshita Sahoo,
  • Ayush Heda,
  • Ravi Shah,
  • Garvita Gulati,
  • Jaya Chaturvedi

摘要

Purpose

The present study was conducted to estimate the incidence of intraoperative and postoperative adverse events in patients undergoing surgery for gynecologic malignancies.

Methods

Preoperative patient characteristics, surgical procedure and disease characteristics were studied for a cohort of patients undergoing surgical management for gynecologic malignancies at AIIMS Rishikesh from 2021 to 2023. The incidence of adverse events and complications was analyzed intraoperatively and postoperatively at seven, fourteen and thirty and graded according to Common Terminological Criteria for Adverse Events 5.0.

Results

The preoperative evaluation was done among 124 patients, out of which 10 were lost to follow-up. One hundred and fourteen patients were finally analyzed. The most common intraoperative adverse event was hemorrhage that led to blood transfusion 29/114 (25.45%), followed by bowel injury 9/114 (7.89%). The most common postoperative complication was also blood transfusion 29/114 (25.45%) followed by wound infection 25/114 (21.93%). The significant independent risk factors associated with adverse events were the patient’s serum albumin and ECOG performance scores more than two. Increased blood loss, ASA grade more than 2 and intermediate surgical complexity score further increased the odds of occurrence of adverse events.

Conclusion

The provision of satisfactory preoperative care and optimization for surgery is a critical step in reducing adverse events and improving patient safety and quality of life in women with gynecologic cancer who are undergoing radical operative procedures. It is necessary to do additional research to identify areas of decreased compliance with guidelines for initiatives to improve adherence to evidence-based medicine practices to be developed.