MiRNA-202 Role in Reproductive System and Gynecological Cancers

期刊论文
发表日期：

2024年5月5日

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Farzaneh Vahedi,
Fatemeh Hasani,
Maryam Rezaee,
Marjan Nourigorji,
Ali Saber Sichani,
Hojat Ghasemnejad‐Berenji,
Mortaza Taheri-Anganeh,
Seyyed Hossein Khatami,
Kamran Hosseini,
Ahmad Movahedpour,
Mostafa Moazamfard

摘要

Introduction

MicroRNAs, also known as miRNAs, are small regulatory RNAs, and they also include many different types in terms of size and commission that do not code the proteins but are crucial for many biological activities, such as formation, regulation, and inhibition in biological pathways.

miRNA-202

Our aim in this study was to analyze miRNA-202 in reproductive system settings, including the formation and function of reproductive systems. MiRNA-202 has been identified as a tumor suppressor in ovarian, endometrial, and cervical malignancies; in addition, it is essential for follicular growth and oogenesis.

Conclusion

This study reviews the most recent evidence supporting the concept that dysregulation of miRNA-202 may contribute to gynecological malignancies.