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Concomitant Radiochemotherapy: Principles and Biological Foundations

  • Abdelhak Maghous,
  • El-Amin Marnouche,
  • Imane Zakariya,
  • Mouhcine Hommadi,
  • Maroua Belemlih,
  • Noha Zaghba,
  • Ayoub Ennadif,
  • Amine Bazine,
  • Issam Lalya,
  • Khalid Andaloussi Saghir,
  • Mohamed Elmarjany,
  • Khalid Hadadi,
  • Hassan Sifat

摘要

Concomitant radiochemotherapy is the simultaneous administration of radiotherapy and chemotherapy, currently a standard in many locally advanced tumors. Combined treatment can improve therapeutic index of individual treatments. However, it is important to have a good understanding of the mechanisms of interaction, as they may eventually lead to modifications in the modalities of drug administration or irradiation.