Simultaneous Bilateral Yolk Sac Tumors: A Rare Presentation of Mixed Germ Cell Tumors

Yolk sac tumors are rare ovarian malignancies accounting for less than 1% of malignant ovarian germ cell tumors. They are mostly seen in adolescents and young women and are usually unilateral. Raised alpha-feto protein (AFP) level is the hallmark of this tumor.

This case report mentions a young 16-year-old girl with component of yolk sac tumor in bilateral ovarian mixed germ cell tumors, highlighting the diagnostic process, treatment strategy, and positive outcome. A fertility-sparing complete staging surgery was done, and she received four cycles of Bleomycin, Etoposide, Cisplatin (BEP) adjuvant chemotherapy. The prognosis was significantly improved with modern chemotherapy regimens.

The rarity of the bilaterality of this tumor makes this case report an interesting one. The multi-disciplinary approach in management of such young girls with an aggressive type of germ cell tumor is what makes this case report worthy of reporting.