<p>The Desi transgender community in the USA faces numerous problems—routinely stigmatized and isolated in their community and society. The dominant discourse about the transgender community flows from the perspective of their social ostracization, economic marginalization, short life span, mental health, sexual harassment, and other vulnerabilities. Often the transgender community is understood as homogenous, close-knit who have come together because of being driven away from family and society, succumbing to stigmatized livelihood options such as sex work and homelessness. Many trans people of color face the dual discrimination of their race and gender. A war is raging against trans people, doctors, and social workers, who are helping them in their transition. In this sense, transgender persons are often seen as victims who are socially excluded by mainstream society. Their families not accepting them is the most painful experience for them. Recently, many activists have come forward to take up their cause. Several activists and family support groups and their allies are emerging in the role of mentors, extended family, and community, and their efforts are highly illuminating.</p>