<p>This article presents the thermodynamic second law analysis for electrically conducting forced convection flow of a non-Newtonian tangent hyperbolic fluid in a microchannel with parallel permeable plate subjected to constant magnetic field applied transversely to the plates. Walls of the channel are assumed to be heated convectively. Governing equations that describes the proposed problem are formulated and then transformed using non-dimensional variables. Simplified governing equations are numerically solved with the aid of finite element method (FEM). The impact of pertinent flow parameters on velocity, temperature, entropy generation and Bejan number are discussed and visualized graphically. The Eckert and Biot numbers are found to play a signficant role in minimizing irreversibility in the thermal system. Weissenberg number decelerates the flow near the bottom wall but enhancing the flow substantially towards the upper wall of the channel. The Biot number causing increase in entropy generation and Bejan number.</p>