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Comprehensive analysis of mathematical model of HIV/AIDS incorporating fisher-folk community

  • Syeda Alishwa Zanib,
  • Sehrish Ramzan,
  • Muzamil Abbas Shah,
  • Nadeem Abbas,
  • Wasfi Shatanawi

摘要

The Human Immunodeficiency Virus (HIV) is a pathogen that specifically targets the human immune system, leading to a more advanced condition known as acquired immunodeficiency syndrome (AIDS) when it significantly compromises the body’s immune defences. In this research, a comprehensive mathematical model for HIV/AIDS has been developed, encompassing the dynamics within both the general population and the fisher-folk population. Utilizing the next-generation matrix method, we calculate the basic reproduction number ( \({R}_{0}\) R 0 ), a crucial metric that quantifies the rate of HIV transmission. Through bifurcation analysis, we have explored the implications of varying \({\eta }^{*}\) η and \({\eta }_{F}^{*}\) η F , serving as bifurcation parameters, at the critical threshold where \({R}_{0}=1\) R 0 = 1 . A sensitivity analysis of the basic reproduction number \({R}_{0}\) R 0 is conducted for both the general community and the fisherfolk community. For the general community, the sensitivity parameters are \(\eta\) η , \({\omega }_{F}\) ω F , \(\phi\) ϕ , and \({\eta }_{F}\) η F . For the fisher-folk community, the sensitivity parameters are \(\eta\) η , \(\omega\) ω , \({\phi }_{F}\) ϕ F , and \({\eta }_{F}\) η F . This analysis enhances our understanding of the factors influencing HIV transmission rates. Using the Routh-Hurwitz criterion and Castillo Chavez's approach, we have demonstrated the HIV-free equilibrium is locally asymptotically stable and globally asymptotically stable when \({R}_{0}<1\) R 0 < 1 , respectively. Furthermore, the research explores the graphical behavior of both the general and fisher-folk communities, providing insights into their respective dynamics.