<p>This paper presents the innovative development of a compact piezo-stack actuator amplifier that effectively combines high load capacity, extended travel range, and a minimal form factor. By integrating a piezo-stack element with a compliant mechanism, the authors enhance the actuator’s displacement capabilities, overcoming the limitations typically associated with miniature actuators. The study identifies a significant gap in the availability of precise, lightweight devices that can exert forces greater than 2&#xa0;N while maintaining a compact structure of less than 1&#xa0;cm³. To address this need, the authors developed an actuator capable of achieving precise motion at a nanometric scale with substantial travel distances, employing iterative simulations and optimization algorithms to establish an efficient operating principle. Additionally, an in-house measurement station was meticulously crafted to evaluate the actuator’s performance with nanometric accuracy. Experimental results show a maximum hysteresis value of no more than 9.7% and open-loop drift below 1%, aligning with industry standards. This innovative actuator design not only fills a critical gap in high-precision, lightweight solutions but also demonstrates significant potential for applications in small observational telescopes, particularly in space settings. By addressing the need for high-precision positioning, this work contributes valuable advancements to the field of miniature piezoelectric actuators and paves the way for next-generation optical component manipulation.</p>