Background <p>The wide range of possible career choices in the medical field holds both opportunities and challenges. This study investigates which specialties German medical students in their third-year year are considering to take on and investigates differences between students studying in a traditional versus in a reformed curriculum.</p> Methods <p>An online multicentre survey was conducted at 23 German medical schools, resulting in 334 participants. A self-constructed questionnaire, which was created by medical experts, was used to examine sociodemographic details and details regarding the curriculum that the participant was enrolled in.</p> Results <p>Anesthesiology and intensive care medicine was the most popular specialty among the sample, followed by surgical specialties and internal medicine. Females were more likely to choose obstretics and gynecology while the opposite was the case for internal medicine, which was preferred by male students. Primary care and general medicine was more popular among those students enrolled in a traditional curriculum, compared to those enrolled in reformed curriculum.</p> Conclusion <p>The gender differences are line with previous research. The difference between the two types of curricula could be due to the characteristics of the curricula, such as differences in the timing and amount of practical experiences.</p>