Background and objective <p>Hybrid forms of work, in which employees carry out their tasks partly in presence (e.g., in the office) and partly in a&#xa0;flexible mobile way (e.g., working from home), are omnipresent. However, the transition to hybrid forms of work is often associated with challenges such as a&#xa0;strong culture of presence and an inadequate technical infrastructure. Comprehensive scientific findings on the relationship between hybrid working conditions and employee health are still required. This literature review aims to identify the psychosocial job demands and resources in the hybrid work context to support the design of healthy working conditions.</p> Methods <p>In an exploratory literature search, study results are presented on job demands and resources that arise in the context of hybrid working. Based on key terms and predefined inclusion and exclusion criteria, 30 studies were included following a content and method review.</p> Results <p>Study results present numerous psychosocial work requirements in the context of hybrid working, e.g., work organization, special features of the working environment and influences on the organization of social relationships as well as a variety of work resources that can result from hybrid working, e.g. an extended scope for action and decision-making.</p> Conclusion <p>This review offers an insight into the psychosocial work demands and resources of hybrid work, thereby providing a foundation for further research to understand the impact of hybrid working conditions on employee health-related outcomes. The recommendations for action outlined provide a&#xa0;valuable reference point for health-promoting hybrid working conditions that employers should incorporate into the ongoing transition to hybrid work as early as possible.</p>