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<p>Precocious puberty is the development of secondary sexual characteristics before the age of 8 in girls and 9 in boys. It can be central or peripheral, with a genetic, organic, or multifactorial aetiology. In recent years, an increase in cases has been observed, especially in girls. Early diagnosis and targeted therapy, such as GnRH analogues, are essential to preserve patients’ height and psychological well-being.</p>

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Pubertà precoce: approccio diagnostico e terapeutico

  • 期刊论文

  • 发表日期：

    2026年3月12日

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  • Gaia Pietropaolo,
  • Marialaura Longobardi,
  • Anna Grandone

摘要

Precocious puberty is the development of secondary sexual characteristics before the age of 8 in girls and 9 in boys. It can be central or peripheral, with a genetic, organic, or multifactorial aetiology. In recent years, an increase in cases has been observed, especially in girls. Early diagnosis and targeted therapy, such as GnRH analogues, are essential to preserve patients’ height and psychological well-being.