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<p>Central insipidus, also known as arginine vasopressin deficiency, is a complex clinical condition that can be caused by several congenital and/or acquired hypothalamic-pituitary disorders. This article provides a practical overview of the condition, from aetiology to diagnostic workup, focusing on the usefulness of copeptin and the importance of brain MRI, to the management. We also highlight several pitfalls that may complicate the differential diagnosis of conditions presenting with polyuria and polydipsia.</p>

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Il diabete insipido centrale (difetto di vasopressina) in età pediatrica

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年11月7日

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  • Giuseppa Patti,
  • Rosa Fumo,
  • Flavia Napoli,
  • Mohamad Maghnie,
  • Natascia Di Iorgi

摘要

Central insipidus, also known as arginine vasopressin deficiency, is a complex clinical condition that can be caused by several congenital and/or acquired hypothalamic-pituitary disorders. This article provides a practical overview of the condition, from aetiology to diagnostic workup, focusing on the usefulness of copeptin and the importance of brain MRI, to the management. We also highlight several pitfalls that may complicate the differential diagnosis of conditions presenting with polyuria and polydipsia.