<p>Historically, malnutrition has been considered either an insufficient or inappropriate nutrient intake, thus playing a key role in clinical diagnoses related to glycolipidic dysmetabolism. As a necessary and sufficient evidence to a parsimonious diagnostic reasoning, it emerges as a relevant factor for diagnosis of malnutrition-related diabetes, a glycolipidic disorder traced back to the early 20th century, now very timely in Italy in relation to the immigration from countries where it was originally identified (Africa, Asia). Described in Jamaica at the half of the 20th century as diabetes J, it resulted as a “hybrid” between diabetes Type 1 and 2 in underweight young subjects, recently found having phenotypic similarities with normal-weight metabolically-unhealthy people. Leading to ketosis only rarely, it requires high insulin doses, it does not associate with steatotic liver disease, it might favourably respond to high-protein diet and combined therapy with insulin and oral hypoglycaemic agents, and, this year, the International Diabetes Federation classified it as Type 5 diabetes mellitus.</p>

错误:搜索内容不能为空,请输入英文关键词
错误:关键词超出字数限制,请精简
高级检索

Il diabete mellito J o Tipo 5: un vecchio problema clinico nella nuova medicina delle migrazioni e degli stili di vita

  • Roberto Toni,
  • Fulvio Barbaro,
  • Giusy Di Conza,
  • Francesca Pia Quartulli,
  • Salvatore Mosca,
  • Massimiliano Mosca

摘要

Historically, malnutrition has been considered either an insufficient or inappropriate nutrient intake, thus playing a key role in clinical diagnoses related to glycolipidic dysmetabolism. As a necessary and sufficient evidence to a parsimonious diagnostic reasoning, it emerges as a relevant factor for diagnosis of malnutrition-related diabetes, a glycolipidic disorder traced back to the early 20th century, now very timely in Italy in relation to the immigration from countries where it was originally identified (Africa, Asia). Described in Jamaica at the half of the 20th century as diabetes J, it resulted as a “hybrid” between diabetes Type 1 and 2 in underweight young subjects, recently found having phenotypic similarities with normal-weight metabolically-unhealthy people. Leading to ketosis only rarely, it requires high insulin doses, it does not associate with steatotic liver disease, it might favourably respond to high-protein diet and combined therapy with insulin and oral hypoglycaemic agents, and, this year, the International Diabetes Federation classified it as Type 5 diabetes mellitus.