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Presupposti fisiopatologici e aspetti pratici della supplementazione con vitamina D in associazione con le terapie anti-riassorbitive nell’osteoporosi

  • Luigi di Filippo,
  • Umberto Terenzi,
  • Fabio Massimo Ulivieri,
  • Mauro Doga,
  • Andrea Giustina

摘要

Osteoporosis is a systemic skeletal disease with an increasing incidence and prevalence in our population, and anti-resorptive drugs are a cornerstone of its medical treatment. However, in the very common condition of hypovitaminosis D the effect of these treatments is suboptimal. In this brief-review, we aimed to present the pathophysiological basis and practical aspects of vitamin D supplementation in combination with anti-resorptive therapies in osteoporosis.