Il rischio tromboembolico nella sindrome dell’ovaio policistico

Hyperandrogenism and the hormonal alterations that sustain menstrual cycle disorders appear, together with obesity and altered insulin status, to expose PCOS patients to a hypercoagulative state. This phenomenon, mainly involving secondary haemostasis, increase the risk of venous thromboembolism up to 2 times in PCOS when compared to the general population. However, the epidemiological data available are the result of studies derived from both selected cohorts or registry studies, so producing biases that cannot be overlooked in the interpretation of these results. Finally, to date, literature on the use of contraceptive pill and PCOS does not include the most recent formulations.