<p>Previous studies have demonstrated the utility of multi-component interventions for the treatment of interfering motor stereotypy. However, less is known about contraindications to established treatment procedures when stereotypy is multiply maintained. The current study evaluated the effects of an empirically derived, caregiver-implemented response reduction procedure on motor stereotypy in a child with autism using a withdrawal design. Results suggested reductions in motor stereotypy from baseline (<i>M</i> = 93%), with caregivers reporting high acceptability regarding the efficacy and feasibility of the approach.</p><p> • Stereotypic behavior deemed as functionally impairing may be considered as a target for behavior analytic treatment. Caregivers can be important partners for making this determination.</p><p> • Motor stereotypy is often assumed to be maintained by automatic reinforcement; however, the use of functional analysis is essential to confirm function and determine the most appropriate course of treatment.</p><p> • Incorporating caregiver input about treatment procedures prior to their being programmed is as useful for collaboration around family values as it is for ensuring the generality and durability of outcomes.</p>