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Background <p>Proximal femur fractures (PFF) are the most common fracture type worldwide, particularly in geriatric patients. Despite advancement in treatment, mortality rates in this patient group remain high.</p> Aims <p>The aim of this study was to analyze potential factors, influencing the 90-day mortality rate and complication rate after PFF surgery in a tertiary care hospital.</p> Methods <p>Between 2019 and 2022, all patients aged 65 and older with PFF and a positive screening as a geriatric patient were included in this prospective, single-center study. Data collected included gender, age, BMI, fracture type, type and timing of surgery, comorbidities, medication, mobilization and blood loss as well as complications and 90-day mortality.</p> Results <p>Out of 1217 analyzed geriatric patients, 61% underwent surgery within 24&#xa0;h. The complication rate was 21.7% with 3% surgical and 20.2% non-surgical complications. Median age was 87 years and 68% were female, while mean Charlson Comorbidity Index was 2.6 points and 84% had ASA 3 or 4. 240 patients (19.7%) died within 90 days after surgery. Higher mortality rates were associated with male gender (OR 1.341), higher age (OR 1.093), lower BMI (OR 0.946), higher Charlson Comorbidity Index (OR 1.202), non-surgical complications (OR 2.541) and if mobilization was impossible (OR 10.013). A delay of surgery beyond 24&#xa0;h after admission was associated with the development of wound infections (<i>p</i> = 0.022) and internal medicine-related complications (<i>p</i> = 0.002).</p> Discussion <p>While no correlation was found between surgery timing and 90 days mortality, delays in surgery were associated with adverse effects, including wound infections and internal medicine complications.</p> Conclusion <p>The mortality rates of patients suffering from PFF maintain high and are mainly influenced by non-modifiable patient-related factors.</p> Clinical trials registration <p>German Registry for Clinical Trials, ID: DRKS00034048, date of registration: 10.02.2025. Retrospectively registered.</p>

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Unveiling the hidden risks: 90-day mortality and complications in older adults with proximal femur fractures

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月19日

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  • Clemens Roitzsch,
  • Franziska Beyer,
  • Klaus-Dieter Schaser,
  • Roman Riedel,
  • Marcel Mäder,
  • Anne Postler

摘要

Background

Proximal femur fractures (PFF) are the most common fracture type worldwide, particularly in geriatric patients. Despite advancement in treatment, mortality rates in this patient group remain high.

Aims

The aim of this study was to analyze potential factors, influencing the 90-day mortality rate and complication rate after PFF surgery in a tertiary care hospital.

Methods

Between 2019 and 2022, all patients aged 65 and older with PFF and a positive screening as a geriatric patient were included in this prospective, single-center study. Data collected included gender, age, BMI, fracture type, type and timing of surgery, comorbidities, medication, mobilization and blood loss as well as complications and 90-day mortality.

Results

Out of 1217 analyzed geriatric patients, 61% underwent surgery within 24 h. The complication rate was 21.7% with 3% surgical and 20.2% non-surgical complications. Median age was 87 years and 68% were female, while mean Charlson Comorbidity Index was 2.6 points and 84% had ASA 3 or 4. 240 patients (19.7%) died within 90 days after surgery. Higher mortality rates were associated with male gender (OR 1.341), higher age (OR 1.093), lower BMI (OR 0.946), higher Charlson Comorbidity Index (OR 1.202), non-surgical complications (OR 2.541) and if mobilization was impossible (OR 10.013). A delay of surgery beyond 24 h after admission was associated with the development of wound infections (p = 0.022) and internal medicine-related complications (p = 0.002).

Discussion

While no correlation was found between surgery timing and 90 days mortality, delays in surgery were associated with adverse effects, including wound infections and internal medicine complications.

Conclusion

The mortality rates of patients suffering from PFF maintain high and are mainly influenced by non-modifiable patient-related factors.

Clinical trials registration

German Registry for Clinical Trials, ID: DRKS00034048, date of registration: 10.02.2025. Retrospectively registered.