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<p>In this study, Au colloids have been prepared through pulsed laser ablation (PLA) of a high-purity Au plate immersed in deionized water. Pulsed Q-switched Nd: YAG has been employed to ablate the Au surface throughout ablation. The laser had a frequency of 6&#xa0;Hz, a wavelength of 1064&#xa0;nm, and a constant energy of 250&#xa0;mJ in 300 laser pulses. Synthesized Au particles have been characterized optically through UV-visible spectroscopy, structurally using X-ray diffraction (XRD) analysis, and morphologically through field emission scanning electron microscopy (FE-SEM). The prepared Au nanoparticles (NPs) had an average crystalline size of 24.6&#xa0;nm. The AuNPs had a spherical shape with an average particle size of 29&#xa0;nm, and the surface plasma resonance was centered at 550&#xa0;nm. The impact of AuNPs on the levels of CK in the blood of male rats was investigated. Compared to the control group, treating rats with varying doses of AuNPs revealed variations in creatine kinase. As the AuNPs doses increase, the CK levels in the blood increase.</p>

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The Effect of Synthesized Gold Nanoparticles by Laser Ablation Method on Levels of Creatine Kinase Activity

  • 期刊论文

  • 发表日期：

    2025年1月6日

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  • Hamsa A. Ali,
  • Omar O. Abdulhadi,
  • Jamal M. Rzaij

摘要

In this study, Au colloids have been prepared through pulsed laser ablation (PLA) of a high-purity Au plate immersed in deionized water. Pulsed Q-switched Nd: YAG has been employed to ablate the Au surface throughout ablation. The laser had a frequency of 6 Hz, a wavelength of 1064 nm, and a constant energy of 250 mJ in 300 laser pulses. Synthesized Au particles have been characterized optically through UV-visible spectroscopy, structurally using X-ray diffraction (XRD) analysis, and morphologically through field emission scanning electron microscopy (FE-SEM). The prepared Au nanoparticles (NPs) had an average crystalline size of 24.6 nm. The AuNPs had a spherical shape with an average particle size of 29 nm, and the surface plasma resonance was centered at 550 nm. The impact of AuNPs on the levels of CK in the blood of male rats was investigated. Compared to the control group, treating rats with varying doses of AuNPs revealed variations in creatine kinase. As the AuNPs doses increase, the CK levels in the blood increase.