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Purpose of Review <p>Oxygen-ozone therapy (OOT) is increasingly applied due to its multiple therapeutic effects, but it is still controversial in the medical community. This review provides a comprehensive overview of the recent clinical literature on OOT in dentistry, exploring its efficacy and current issues.</p> Recent Findings <p>OOT has a wide range of applications in dentistry, including caries management, endodontics, periodontics, and oral surgery. Overall, the results are promising with very limited adverse effects. The formulations used include gaseous ozone, ozonized water, ozonized gel, and ozonization of various products. A large methodologic heterogeneity currently prevents definitive conclusions and meaningful comparisons between different protocols.</p> Summary <p>Although not conclusive, current evidence suggests that OOT may offer some advantages as an adjunctive or alternative treatment option in certain clinical conditions. Future research should aim to standardize the reporting methodology of OOT protocols in order to make meaningful comparisons and guide the selection of the best protocols for specific treatment endpoints.</p>

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Ozone in Dentistry: An Updated Overview of Current Applications and Future Perspectives

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年1月14日

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  • Federica Veneri,
  • Valentina Lanteri,
  • Ugo Consolo,
  • Vittorio Checchi,
  • Luigi Generali

摘要

Purpose of Review

Oxygen-ozone therapy (OOT) is increasingly applied due to its multiple therapeutic effects, but it is still controversial in the medical community. This review provides a comprehensive overview of the recent clinical literature on OOT in dentistry, exploring its efficacy and current issues.

Recent Findings

OOT has a wide range of applications in dentistry, including caries management, endodontics, periodontics, and oral surgery. Overall, the results are promising with very limited adverse effects. The formulations used include gaseous ozone, ozonized water, ozonized gel, and ozonization of various products. A large methodologic heterogeneity currently prevents definitive conclusions and meaningful comparisons between different protocols.

Summary

Although not conclusive, current evidence suggests that OOT may offer some advantages as an adjunctive or alternative treatment option in certain clinical conditions. Future research should aim to standardize the reporting methodology of OOT protocols in order to make meaningful comparisons and guide the selection of the best protocols for specific treatment endpoints.