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Purpose of Review <p>In this review, an exploration of the biopolymer; carrageenan (CGN) has been provided with focus on elucidating its biological activities and the applications of its hydrogels in drug delivery, wound healing and tissue engineering.</p> Recent Findings <p>Biomaterials are known substantial building blocks for regenerative medicine, drug delivery and tissue engineering. Amongst these, polymeric biomaterials have greater promise because of the versatility of their properties. CGN, a linear sulfated polysaccharide obtainable from seaweed and its associated hydrogels are promising candidates for several biomedical applications including wound healing, drug delivery and tissue engineering. Unique gelling mechanism, strong negative charge, strong water absorption property and the presence of several functional groups are the properties that project this biopolymer as suitable for these applications. The outlined properties notwithstanding, CGN like most biomaterials has some limitations including the uncontrollable exchange of ions in its hydrogels. The presence of functional groups on the polysaccharide provides an opportunity for its chemical modification; these modifications enhance the physicochemical properties of the hydrogels.</p> Summary <p>The seaweed- derived CGN has several applications in the biomedical industry for tissue engineering, drug delivery and wound healing due to its outstanding inherent properties. Its applicability as well as those of it hydrogels can be enhanced by chemical modifications.</p>

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Exploring Carrageenan: Biological Activities and Applications in Drug Delivery and Tissue Engineering

  • 期刊论文

  • 发表日期：

    2025年5月13日

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  • Great Iruoghene Edo,
  • Agatha Ngukuran Jikah,
  • Egwaedafe Marvellous Elooghene,
  • Splendour Oberhiri Oberhiri,
  • Emad Yousif,
  • Tayser Sumer Gaaz,
  • Endurance Fegor Isoje,
  • Joseph Oghenewogaga Owheruo,
  • Patrick Othuke Akpoghelie,
  • Ufuoma Augustina Igbuku,
  • Dina S. Ahmed,
  • Arthur Efeoghene Athan Essaghah,
  • Huzaifa Umar

摘要

Purpose of Review

In this review, an exploration of the biopolymer; carrageenan (CGN) has been provided with focus on elucidating its biological activities and the applications of its hydrogels in drug delivery, wound healing and tissue engineering.

Recent Findings

Biomaterials are known substantial building blocks for regenerative medicine, drug delivery and tissue engineering. Amongst these, polymeric biomaterials have greater promise because of the versatility of their properties. CGN, a linear sulfated polysaccharide obtainable from seaweed and its associated hydrogels are promising candidates for several biomedical applications including wound healing, drug delivery and tissue engineering. Unique gelling mechanism, strong negative charge, strong water absorption property and the presence of several functional groups are the properties that project this biopolymer as suitable for these applications. The outlined properties notwithstanding, CGN like most biomaterials has some limitations including the uncontrollable exchange of ions in its hydrogels. The presence of functional groups on the polysaccharide provides an opportunity for its chemical modification; these modifications enhance the physicochemical properties of the hydrogels.

Summary

The seaweed- derived CGN has several applications in the biomedical industry for tissue engineering, drug delivery and wound healing due to its outstanding inherent properties. Its applicability as well as those of it hydrogels can be enhanced by chemical modifications.