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Purpose <p>To determine the efficacy of ultrasound (US)-guided bone marrow biopsy technique.</p> Methods <p>The study retrospectively analyzed patients who underwent percutaneous bone marrow core biopsy and aspiration at a single institution from January 2017 to June 2024. Success metrics included lack of patient grievances, precision of sample acquisition, and technical procedural success.</p> Results <p>A sample population of 254 was composed of 150 males (median age of 63&#xa0;years) and 104 females (median age of 63&#xa0;years). The median (range) BMI was 27.08 (15.31–50.17) for males and 28.79 (17.17–54) for females. The technique achieved 100% accuracy rate with no procedure failures or adverse events reported. Samples collected were viable for pathology assessment. Procedure times ranged from 5 to 30&#xa0;min. The biopsy was used in various diagnosis of histopathological disease processes. There were no reported dry taps on aspiration.</p> Conclusion <p>US-guided percutaneous bone marrow biopsy and aspiration emerges as a promising technique, offering numerous advantages over traditional palpated landmark, fluoroscopic and CT-guided approaches. With its ability to provide real-time guidance, avoidance of ionizing radiation, and comprehensive evaluation of adjacent soft tissues and neurovascular structures, US-guided bone biopsy holds significant promise as an alternative to earlier methods.</p>

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Enhancing conventional biopsies: ultrasound-guided percutaneous bone marrow biopsy and aspiration

  • 期刊论文

  • 发表日期：

    2026年3月17日

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  • Caroline Cushman,
  • Alex Smith,
  • Karter Morris,
  • Lauren Dodson,
  • Andrew F. Ibrahim,
  • Evan J. Hernandez,
  • Brendan J. MacKay,
  • Thomas Callahan,
  • Mohammed Attaya

摘要

Purpose

To determine the efficacy of ultrasound (US)-guided bone marrow biopsy technique.

Methods

The study retrospectively analyzed patients who underwent percutaneous bone marrow core biopsy and aspiration at a single institution from January 2017 to June 2024. Success metrics included lack of patient grievances, precision of sample acquisition, and technical procedural success.

Results

A sample population of 254 was composed of 150 males (median age of 63 years) and 104 females (median age of 63 years). The median (range) BMI was 27.08 (15.31–50.17) for males and 28.79 (17.17–54) for females. The technique achieved 100% accuracy rate with no procedure failures or adverse events reported. Samples collected were viable for pathology assessment. Procedure times ranged from 5 to 30 min. The biopsy was used in various diagnosis of histopathological disease processes. There were no reported dry taps on aspiration.

Conclusion

US-guided percutaneous bone marrow biopsy and aspiration emerges as a promising technique, offering numerous advantages over traditional palpated landmark, fluoroscopic and CT-guided approaches. With its ability to provide real-time guidance, avoidance of ionizing radiation, and comprehensive evaluation of adjacent soft tissues and neurovascular structures, US-guided bone biopsy holds significant promise as an alternative to earlier methods.