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<p>A 64-year-old man presented with a palpable, soft, compressible, superficial mass on his left lateral hindfoot, with no other symptoms. No significant past medical history. Initial ultrasound and magnetic resonance imaging (MRI) studies characterized the mass as a cyst-like, fluid-containing lesion. Biopsy results indicated an atypical myxoid and spindle cell neoplasm, with immunohistochemistry favoring “pauci-hemosiderotic” fibrolipomatous tumor. Four months after the biopsy, follow-up MRI revealed substantial tumor size regression with decreased post contrast enhancement. Given the potential for recurrence and malignant transformation in hemosiderotic fibrolipomatous tumors, continuous monitoring and complete surgical excision are recommended.</p>

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Spontaneous regression of “pauci-hemosiderotic” fibrolipomatous tumor

  • 期刊论文

  • 发表日期：

    2025年7月26日

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  • Alejandro Arbona-Lampaya,
  • Kumarasen Cooper,
  • Jenny T. Bencardino

摘要

A 64-year-old man presented with a palpable, soft, compressible, superficial mass on his left lateral hindfoot, with no other symptoms. No significant past medical history. Initial ultrasound and magnetic resonance imaging (MRI) studies characterized the mass as a cyst-like, fluid-containing lesion. Biopsy results indicated an atypical myxoid and spindle cell neoplasm, with immunohistochemistry favoring “pauci-hemosiderotic” fibrolipomatous tumor. Four months after the biopsy, follow-up MRI revealed substantial tumor size regression with decreased post contrast enhancement. Given the potential for recurrence and malignant transformation in hemosiderotic fibrolipomatous tumors, continuous monitoring and complete surgical excision are recommended.