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Use of Predictive Models to Determine Transplant Eligibility

  • Samuel I. Berchuck,
  • Nrupen Bhavsar,
  • Tyler Schappe,
  • Hamed Zaribafzadeh,
  • Roland Matsouaka,
  • Lisa M. McElroy

摘要

Purpose of Review

This paper summarizes predictive models developed to determine transplant eligibility over the past 5 years, focusing on application of novel data sources and methodologic approaches.

Recent Findings

The contemporary body of research employing predictive models to inform transplant eligibility mainly relies on pre- or post-transplant patient survival. No studies have sought to assimilate all features collected during the transplant evaluation process to produce a composite prediction of post-transplant success or failure.

Summary

Predictive modeling is a commonly used statistical technique that uses available data on a subset of a target population to estimate the current health state or the probability of developing a future health outcome among individuals in the target population. Modern analytic techniques allow for transformation of vast amounts of data into actionable information but require curated organized well-defined data to deploy. That data is currently lacking for patients referred for transplant.