<p>This research presents the experimental methodology, digital image processing procedure, computational fluid dynamics (CFD) simulations, and the results obtained from an oil spill experiment in a circulation channel. The experiment simulates a pipe oil leakage and involves releasing red-dyed soybean oil close to the bottom of the circulation channel operating in a laminar flow. The results from the experimental procedure and digital processing are compared with the results from CFD simulations of the oil spill. The methodology involves multiphase flow experiments and simulations, digital image analysis, and verification and validation procedures. The primary parameters of the oil flow are obtained through digital processing and includes the oil trajectory, rising velocity, oil particle size and shape, flow-induced instabilities, and time of residence of the oil in the water column. The image calibration is fundamental for the accuracy and is performed prior to each experiment. The calibration determines the parameters of the lens and of the image sensor, using a checkerboard-type planar target. The experimental results contributed to the CFD solver setup and to validate the procedure for simulating pipe oil leakages. The combined experimental and CFD procedure demonstrates satisfactory accuracy in simulating the oil spill and offers the advantage of being a cost-effective method.</p>