<p>Hybrid multi-cell(HMC) thin-walled structures have been proven to be an efficient energy absorber with high absorption capability and well-controlled deformation stability. In this paper, four types of HMC tubes with different cross-sections and ribs connection method are designed, which are inspired by the microstructure of spider webs. Axial compression experiments and numerical analysis are carried out to characterize the effects of the energy absorption and crushing deformation. Moreover, the mean crushing force of the thin-walled structures are validated by simplified super folding element (SSFE) theory. The results show that the HMC structure of inner circle and outer hexagon cross-section with ribs connect to middle of outside tube (HC2) has the better crashing performance than other three HMC tubes, which impress by 13.64%. Crashworthiness index comparisons show that hierarchical layer N and inner circle diameter d of HC2 tubes can significantly affect the energy absorption ability. The comparison of the impact resistance index shows that the thin-walled tube with a third-order layered structure significantly improves its energy absorption capacity. While the specific energy absorption increases by 21.53%, the ultimate contact force decreases by 3.41%. Compared to other conventional tubes, the spider web cross-section tube maintains good deformation patterns and energy absorption advantages. The newly designed spider web structure thin-walled tube has a maximum increase of 31.82% in energy absorption compared to the previous structure.</p>