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Purpose of Review <p>To explore the effects of inhibitory control on exercise and individuals with methamphetamine use disorder (MUD) and its regulatory mechanisms, to integrate an effective exercise prescription to promote MUD addiction withdrawal, and to provide theoretical and practical guidance for the future of exercise addiction treatment.</p> Recent Findings <p>The results demonstrated that exercise significantly improved inhibitory control levels among individuals with MUD (g= -0.27; 95% CI [-0.46, -0.08], PI [-0.95,0.41], p = 0.006,Moderate quality). Subgroup analysis revealed that the subgroup undertaking exercise sessions of ≤ 30 minutes exhibited a larger effect size (g = −0.61; 95% CI [−1.02,−0.20],PI [-6.18,1.54] p = .0036). Moreover, moderate-intensity exercise was associated with the most pronounced improvement in inhibitory control (g = −0.56; 95% CI [−0.82, −0.30], p &lt; .0001).The results indicated a statistically significant effect of exercise on reducing drug craving(g = -2.32; 95% CI [-3.45,-1.18], p &lt; 0.0001,Moderate quality).</p> Summary <p>Exercise interventions indirectly and effectively reduced drug cravings in individuals with drug dependence by enhancing inhibitory control. This craving reduction exhibited a dose-dependent relationship with both the duration and intensity of the individual exercise programs.</p>

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Can Exercise Alleviate Drug Craving by Enhancing Inhibitory Control? A Systematic Review and Meta-analysis

  • 期刊论文

  • 发表日期：

    2026年3月7日

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  • Yi Yang,
  • Zhu Gui,
  • Henghao Yan,
  • Kun Wang,
  • Changhong Wu,
  • Tingran Zhang,
  • Jiong Luo

摘要

Purpose of Review

To explore the effects of inhibitory control on exercise and individuals with methamphetamine use disorder (MUD) and its regulatory mechanisms, to integrate an effective exercise prescription to promote MUD addiction withdrawal, and to provide theoretical and practical guidance for the future of exercise addiction treatment.

Recent Findings

The results demonstrated that exercise significantly improved inhibitory control levels among individuals with MUD (g= -0.27; 95% CI [-0.46, -0.08], PI [-0.95,0.41], p = 0.006,Moderate quality). Subgroup analysis revealed that the subgroup undertaking exercise sessions of ≤ 30 minutes exhibited a larger effect size (g = −0.61; 95% CI [−1.02,−0.20],PI [-6.18,1.54] p = .0036). Moreover, moderate-intensity exercise was associated with the most pronounced improvement in inhibitory control (g = −0.56; 95% CI [−0.82, −0.30], p < .0001).The results indicated a statistically significant effect of exercise on reducing drug craving(g = -2.32; 95% CI [-3.45,-1.18], p < 0.0001,Moderate quality).

Summary

Exercise interventions indirectly and effectively reduced drug cravings in individuals with drug dependence by enhancing inhibitory control. This craving reduction exhibited a dose-dependent relationship with both the duration and intensity of the individual exercise programs.