Purpose of Review <p>Sleep disorders are a common issue among patients undergoing methadone treatment, which can influence the treatment process and at treatment outcomes. Therefore, this study aims to determine the prevalence of sleep disorders in patients receiving methadone treatment through a systematic review and meta-analysis.</p> Recent Findings <p>Sleep problems are common in patients undergoing methadone treatment for drug dependence, according to recent studies. Methadone, a medication used to treat drug dependence, can cause side effects like insomnia, sleep apnea, and excessive sleepiness (hypersomnia). These sleep issues can disrupt the treatment process. Research indicates that a significant number of patients in methadone maintenance treatment (MMT) experience sleep disorders. It is estimated that 50 to 80 percent of these patients may be affected by sleep disorders such as insomnia, hypersomnia, and sleep apnea.</p> Summary <p>The reviewed evidence clearly points to a high prevalence of sleep disorders among clients undergoing methadone treatment. Numerous studies have consistently demonstrated that individuals in methadone programs frequently experience various sleep-related issues. These include poor sleep quality, where individuals report not feeling rested even after a full night's sleep, and insomnia, characterized by difficulty falling or staying asleep. Furthermore, conditions like obstructive sleep apnea (OSA), a disorder causing interrupted breathing during sleep, and excessive daytime sleepiness are also commonly observed in this population. Therefore, sleep disorders in methadone-treated clients represent a significant challenge that can profoundly affect their overall well-being. These sleep disturbances can negatively impact their quality of life, making it harder to enjoy daily activities and maintain a sense of normalcy.</p>