Introduction <p>Incidental breast findings on PET imaging, though uncommon, are increasingly reported with the expanding use of non-[¹⁸F]FDG radiotracers in various oncologic settings. This pictorial essay illustrates a range of such lesions, emphasizing potential diagnostic pitfalls and highlighting the importance of accurate interpretation in clinical practice.</p> Methods <p>We collected clinical BC cases from two high-volume PET/CT clinical centres. Each centre checked its database to identify breast lesions detected on PET/CT performed with tracers different from [¹⁸F]FDG. Afterward, the chosen cases were reviewed collectively by the authors, with emphasis placed on those considered to have significant clinical relevance.</p> Results <p>Following the screening process, four clinical cases were identified. The selected cases demonstrate a diverse range of benign and malignant findings on [¹¹C]methionine, [¹⁸F]PSMA-1007, [⁶⁸Ga]Ga-Pentixafor and [⁶⁸Ga]Ga-DOTATOC, including a suspicious uptake (further follow-up is needed), a myofibroblastoma, a bifocal invasive ductal carcinoma of no special type, and a case of benign breast lesion with fibrocystic changes.</p> Conclusions <p>These cases highlight the diverse PET imaging appearances of breast lesions detected with non-[¹⁸F]FDG tracers. Imaging and histopathological correlations are essential to avoid misdiagnosis.</p>