<p>The current anti-doping framework, particularly the absolute prohibition of substances like Clostebol without any threshold, raises serious concerns about fairness, scientific integrity, and the practical enforcement of regulations. This letter presents a comprehensive argument against the inconsistent treatment of substances with high contamination potential, such as Clostebol, which are penalized at trace levels, while other substances that may have greater performance-enhancing effects are permitted within set thresholds. The current zero-tolerance approach to Clostebol, despite its significant risk of inadvertent exposure, is both scientifically unsound and ethically unjust. It creates disparities in anti-doping policies, unfairly punishes athletes for unintentional contamination, and fails to&#xa0;adequately&#xa0;address substances with a stronger potential for performance enhancement. By establishing reasonable thresholds for high-risk substances, continuously updating the prohibited list based on emerging scientific evidence, and adopting a risk-based strategy, anti-doping agencies can foster a more just and effective system, one that upholds the integrity of sport while recognizing the realities of inadvertent exposure.</p>

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The case for revisiting anti-doping policies on substances with high contamination risk (e.g., Clostebol)

  • Alberto Boretti

摘要

The current anti-doping framework, particularly the absolute prohibition of substances like Clostebol without any threshold, raises serious concerns about fairness, scientific integrity, and the practical enforcement of regulations. This letter presents a comprehensive argument against the inconsistent treatment of substances with high contamination potential, such as Clostebol, which are penalized at trace levels, while other substances that may have greater performance-enhancing effects are permitted within set thresholds. The current zero-tolerance approach to Clostebol, despite its significant risk of inadvertent exposure, is both scientifically unsound and ethically unjust. It creates disparities in anti-doping policies, unfairly punishes athletes for unintentional contamination, and fails to adequately address substances with a stronger potential for performance enhancement. By establishing reasonable thresholds for high-risk substances, continuously updating the prohibited list based on emerging scientific evidence, and adopting a risk-based strategy, anti-doping agencies can foster a more just and effective system, one that upholds the integrity of sport while recognizing the realities of inadvertent exposure.