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<p>Oral lichen planus (OLP) is a potentially very painful immune-mediated inflammatory disease for which there is no cure. Treatment options consist of immunosuppressive, immunomodulatory and anti-inflammatory drugs. Treatment is usually topical. Topical superpotent corticosteroids are the mainstay of treatment, and topical calcineurin inhibitors are suggested for OLP refractory to topical corticosteroids. Beyond these, there is a wide range of additional treatment options. It is necessary to follow-up regularly and monitor for malignancy associated with the disease.</p>

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Consider topical superpotent corticosteroids for oral lichen planus; reserve systemic therapy for severe disease

  • 期刊论文

  • 发表日期：

    2025年3月4日

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  • Esther S. Kim,
  • Simon Fung

摘要

Oral lichen planus (OLP) is a potentially very painful immune-mediated inflammatory disease for which there is no cure. Treatment options consist of immunosuppressive, immunomodulatory and anti-inflammatory drugs. Treatment is usually topical. Topical superpotent corticosteroids are the mainstay of treatment, and topical calcineurin inhibitors are suggested for OLP refractory to topical corticosteroids. Beyond these, there is a wide range of additional treatment options. It is necessary to follow-up regularly and monitor for malignancy associated with the disease.