<p>This novel study focuses on the dissimilar joining of copper-coated Ti-6Al-4V sheets with AZ31B sheets using arc-based joining processes. First, Ti-6Al-4V sheets were coated with copper using electrodeposition. Copper was deposited on the Ti-6Al-4V alloy to promote the intermetallic formation at the joint interface between the AZ31B weld zone and the Ti-6Al-4V alloy zone to assist the metallurgical bonding between the AZ31B weld zone and the Ti-6Al-4V. AZ31B and copper-coated Ti-6Al-4V sheets were joined using cold metal transfer welding. Joints were fabricated at heat inputs of 36.96 and 39.83 J/mm. Macroscopically, bead profiles processed through both heat inputs were almost similar. However, analyzing the joints microscopically, there is the presence of solidification cracking from the root of the fusion line between the AZ31B weld zone and the AZ31B base metal for the joint obtained at a heat input of 36.96 J/mm, while the joint obtained at a heat input of 39.83 J/mm shows good integrity in microscopic examination as well. In both joints, there is a significant difference in the microstructure of the weld zone and AZ31B base metal regions in terms of the distribution of secondary phase precipitates in the α-Mg matrix. There is a formation of a reaction layer consisting of intermetallics at the interface owing to the effect of copper coating, with higher concentrations of Al and Cu. This study shows a mixed response in terms of the strength of weld joints, where joints with maximum strength can bear a load of 1040.6 N. On the other hand, joints that suffered with poor fusion between AZ31B weld metal and AZ31B base metal have sustained loads only up to 305.77 N.</p>