Combined Effect of Non-Invasive Brain Stimulation with Mirror Therapy for Improving Motor Function in Patients with Stroke: a Systematic Review with Meta-Analysis

期刊论文
发表日期：

2024年5月9日

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Naglaa Abdelhaleem,
Alaa Tawfek,
Hagar S. Abouamra,
Maya G. Aly,
Samar Taher Elbanna,
Amira Galal Mahmoud,
Amal A. Elborady,
Poussy S. Gheitah,
Shorouk Elshennawy

摘要

Purpose of review

This review aimed to evaluate the evidence of using non-invasive brain stimulation (NIBS) combined with mirror therapy (MT) for patients with stroke.

Recent findings

This systematic review included eight RCTs; four of them were of high quality. The meta-analyses revealed a significant effect of NIBS with MT on improving the hand grip strength (P = 0.0010), and gross manual dexterity (P = 0.0002), while sensorimotor function and cortical excitability were not significant. The timing-dependent effect of the tDCS with MT on the sensorimotor function was non-significant.

Summary

Findings of this review emphasize the use of MT in stroke rehabilitation with NIBS to improve hand grip strength and gross manual dexterity. Moderate evidence is present for the effect of transcranial magnetic stimulation with MT on balance and walking, and limited evidence for temporal-spatial gait parameters improvement. More high quality RCTs with longer follow-up are needed to strengthen the present evidence.