Purpose of Review <p>The application of music intervention to enhance the patient’s hospitalization experience has a long-standing history. Music intervention, as a non-pharmacological treatment, is being used in various clinical settings such as wards, outpatient surgical centers, intensive care units (ICU), and surgical theatres. The aim of this review is to summarize the extensive research on the influence of music intervention on perioperative patients. Additionally, we intend to explore the benefits associated with such an intervention.</p> Recent Findings <p>Numerous clinical studies have investigated the impact of music intervention on patient anxiety, pain, hemodynamic variables, depth of sedation, and postoperative recovery. However, due to a multitude of factors, the findings from these studies remain inconsistent.</p> Summary <p>Music intervention is a non-pharmacological treatment widely used in different clinical areas. The accelerated rehab surgery model aims to protect patients from physiological and psychological stress during the perioperative period, reduce postoperative complications, and promote recovery. Although the effects of music intervention on perioperative patients have been studied extensively, the results are still not conclusive. Further research is needed to better understand the role and optimal application of music intervention in the perioperative care of patients.</p>