Apheresis Indications in the Perioperative Setting

This review summarizes the American Society for Apheresis (ASFA) recommendations for apheresis indications in the perioperative setting. It reviews pathophysiology of these indications, highlights the key rationales for apheresis, and examines the current evidence behind the recommendations. This concise review will allow readers to learn about indications and available evidence behind apheresis in the perioperative setting.

Encountered indications in the perioperative setting include heparin induced thrombocytopenia (HIT), desensitization/rejection prophylaxis or treatment of antibody-mediated rejection in solid organ transplants, sickle cell anemia, and thyroid storm.

Apheresis can be utilized as an adjunct therapy for many perioperative indications.