Paranasal Sinus Malignances: Advances in Radiation Treatment Strategies

The management of paranasal/sinonasal malignancies continues to evolve with improvements in surgical techniques, advances in the delivery of radiation therapy, and development of new systemic therapies. We aim to discuss the management of paranasal sinus malignancies, which often involves multimodality therapy, with a primary focus on the radiotherapy aspects of care.

Advances in the delivery of radiation therapy have led to a variety of new strategies for the treatment of paranasal sinus malignancies, often allowing for an improved therapeutic ratio maximizing the dose to the target while reducing the dose to the surrounding normal structures.

Radiation therapy plays a key role in the management of many paranasal sinus malignancies. Continued advances in the delivery of radiation therapy may provide futher improvement in the risk/benefit ratio for radiotherapy as primary, neoadjuvant, or advant treatment in this setting.