Purpose of Review <p>The impact of GLP1 receptor agonist (GLP1-RA) medications on eating disorders is not established in large scale clinical trials with adult or pediatric populations. Whether GLP1-RA improve or worsen eating disorders is an important clinical question. This review integrates emerging evidence and clinical experience to offer guidance for pediatric GLP1-RA prescribing in the context of observed eating disorders or suspected eating disorders. We provide a review of the controversy around prescribing GLP1-RA to children and adolescents, outline existing research on GLP1-RA and eating disorders with adults, review clinical experience with pediatric populations with comorbid eating disorders and obesity treated with GLP1-RA, and provide initial guidance to providers prescribing GLP1-RA in the absence of established research studies.</p> Recent Findings <p>Many children and adolescents will likely benefit from GLP1-RA treatment for Binge Eating Disorder, Night Eating Syndrome, and Other Specified Eating or Feeding Disorder. However, GLP1-RA may have iatrogenic effects with respect to Atypical Anorexia, Bulimia Nervosa, and ARFID.</p> Summary <p>Early data and clinical experience indicate that GLP1-RA are beneficial for some pediatric patients with co-morbid obesity and eating disorders. However, some types of eating disorders could worsen with GLP1-RA and require monitoring and treatment by registered dietitian and/or behavioral health providers who specialize in eating disorders, with appropriate referrals to higher levels of care for disordered eating.</p>

错误:搜索内容不能为空,请输入英文关键词
错误:关键词超出字数限制,请精简
高级检索

GLP1-RA and Pediatric Populations: Psychosocial Issues and Eating Disorder Treatment Approaches for Co-Morbid Obesity and Eating Disorders

  • Susan M. Himes,
  • Stephanie Sogg,
  • Jennifer Lauretti,
  • Noreen A. Reilly-Harrington

摘要

Purpose of Review

The impact of GLP1 receptor agonist (GLP1-RA) medications on eating disorders is not established in large scale clinical trials with adult or pediatric populations. Whether GLP1-RA improve or worsen eating disorders is an important clinical question. This review integrates emerging evidence and clinical experience to offer guidance for pediatric GLP1-RA prescribing in the context of observed eating disorders or suspected eating disorders. We provide a review of the controversy around prescribing GLP1-RA to children and adolescents, outline existing research on GLP1-RA and eating disorders with adults, review clinical experience with pediatric populations with comorbid eating disorders and obesity treated with GLP1-RA, and provide initial guidance to providers prescribing GLP1-RA in the absence of established research studies.

Recent Findings

Many children and adolescents will likely benefit from GLP1-RA treatment for Binge Eating Disorder, Night Eating Syndrome, and Other Specified Eating or Feeding Disorder. However, GLP1-RA may have iatrogenic effects with respect to Atypical Anorexia, Bulimia Nervosa, and ARFID.

Summary

Early data and clinical experience indicate that GLP1-RA are beneficial for some pediatric patients with co-morbid obesity and eating disorders. However, some types of eating disorders could worsen with GLP1-RA and require monitoring and treatment by registered dietitian and/or behavioral health providers who specialize in eating disorders, with appropriate referrals to higher levels of care for disordered eating.