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<p>Despite international standards, the lack of an independent audit system in South Korea has led to quality management challenges in high-dose-rate brachytherapy, prompting the development of a precise source activity measurement system and a regulatory MATLAB code. We developed an audit system that integrates a source strength measurement system and mechanical accuracy check phantoms using a well-type chamber electrometer setup and an in-house MATLAB code. We achieved audit suitability with appropriate uncertainty and compatibility across various&#xa0;Remote After-Loading System (RALS). Our uncertainty assessments revealed the proposed expanded uncertainties (<i>k</i> = 2) of 2.72% and 2.71% for models 70010 and 72280, respectively. Based on these results, we plan to implement this auditing system nationwide to comply with domestic regulations.</p>

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Development of a system for on-site dosimetry audit of high-dose-rate brachytherapy

  • 期刊论文

  • 发表日期：

    2025年3月10日

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  • Hyeok-Jun Gwon,
  • Wonho Lee,
  • Sang-Hyoun Choi,
  • Gyu-Seok Cho,
  • Soon Sung Lee,
  • Sun-Boong Hwang,
  • Kum Bae Kim

摘要

Despite international standards, the lack of an independent audit system in South Korea has led to quality management challenges in high-dose-rate brachytherapy, prompting the development of a precise source activity measurement system and a regulatory MATLAB code. We developed an audit system that integrates a source strength measurement system and mechanical accuracy check phantoms using a well-type chamber electrometer setup and an in-house MATLAB code. We achieved audit suitability with appropriate uncertainty and compatibility across various Remote After-Loading System (RALS). Our uncertainty assessments revealed the proposed expanded uncertainties (k = 2) of 2.72% and 2.71% for models 70010 and 72280, respectively. Based on these results, we plan to implement this auditing system nationwide to comply with domestic regulations.