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<p>Mosquitoes are one of the primary arthropod vectors transmitting various medically important diseases such as West Nile virus, yellow fever, Japanese encephalitis, dengue, chikungunya, Zika, malaria, lymphatic filariasis, and others that are the important mosquito vectors such as <i>Aedes</i>, <i>Anopheles</i>, and <i>Culex</i>. In this state, synthetic larvicides are a popular technique for controlling vector mosquitoes; nevertheless, their extended use may lead to larvicide resistance or tolerance and create environmental issues and adverse consequences for humans and other animals. Consequently, in response to this issue, there has been a growing endeavor to identify alternatives to larvicides. Hence, this review concentrated on naturally occurring phytocompounds, on vector mosquitoes. A total of 40 phytocompounds from 11 plant species belong to 10 families have been identified with larvicidal properties, of the phytocompound studied only few compounds such as cinnamic acid, methyl cinnamate, ethyl cinnamate, propyl cinnamate, isopropyl cinnamate, methoxyethyl cinnamate, butyl cinnamate, pentyl cinnamate, isopentyl cinnamate, hexyl cinnamate, 4-chlorobenzyl cinnamate, benzyl cinnamate, 3-methoxybenzyl cinnamate, rolliniastatin, and β-isocostic acid exhibits highly toxic to <i>Ae. aegypti</i>, <i>An. stephensi,</i> and <i>Cx. quinquefasciatus</i>, prompted by their shown efficacy and the pursuit of more sustainable, eco-friendly, and alternatives to synthetic larvicides.</p> Graphical Abstract <p></p>

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Phytocompounds as Medically Important Mosquito Vector Control Agents: A Review

  • 期刊论文

  • 发表日期：

    2026年7月10日

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  • Kaliyamoorthy Dass,
  • Rengarajan Murugesan,
  • Srinivasan Prabhu

摘要

Mosquitoes are one of the primary arthropod vectors transmitting various medically important diseases such as West Nile virus, yellow fever, Japanese encephalitis, dengue, chikungunya, Zika, malaria, lymphatic filariasis, and others that are the important mosquito vectors such as Aedes, Anopheles, and Culex. In this state, synthetic larvicides are a popular technique for controlling vector mosquitoes; nevertheless, their extended use may lead to larvicide resistance or tolerance and create environmental issues and adverse consequences for humans and other animals. Consequently, in response to this issue, there has been a growing endeavor to identify alternatives to larvicides. Hence, this review concentrated on naturally occurring phytocompounds, on vector mosquitoes. A total of 40 phytocompounds from 11 plant species belong to 10 families have been identified with larvicidal properties, of the phytocompound studied only few compounds such as cinnamic acid, methyl cinnamate, ethyl cinnamate, propyl cinnamate, isopropyl cinnamate, methoxyethyl cinnamate, butyl cinnamate, pentyl cinnamate, isopentyl cinnamate, hexyl cinnamate, 4-chlorobenzyl cinnamate, benzyl cinnamate, 3-methoxybenzyl cinnamate, rolliniastatin, and β-isocostic acid exhibits highly toxic to Ae. aegypti, An. stephensi, and Cx. quinquefasciatus, prompted by their shown efficacy and the pursuit of more sustainable, eco-friendly, and alternatives to synthetic larvicides.

Graphical Abstract