Scholarlink

Background <p>Aeromonas species are increasingly recognized as emerging human pathogens capable of causing a wide spectrum of infections ranging from skin and soft tissue infections to life-threatening bacteremia. Data from India describing their clinical spectrum and antimicrobial resistance patterns remain limited.</p> Methods <p>We conducted a retrospective study of 61 culture-proven cases of Aeromonas infection identified between 2019 and 2025 at a tertiary care centre in South India. Demographic characteristics, clinical presentation, comorbidities, microbiological findings, antimicrobial susceptibility patterns, treatment, and outcomes were analysed.</p> Results <p>The mean patient age was 46 years, and 57% were male. The most common clinical presentations were skin and soft tissue infections (40.9%) and bacteremia (40.9%), while pulmonary and urinary infections were less frequent. Common comorbidities included diabetes mellitus (27.8%) and chronic liver disease (14.7%), and trauma preceded infection in 16.3% of cases. Antimicrobial susceptibility testing showed high resistance to carbapenems, with resistance rates of 54.7% to meropenem and 27.8% to imipenem. In contrast, cephalosporins largely retained activity. Overall, 81.9% of patients recovered, whereas the mortality rate was 13.1%</p> Conclusion <p>Aeromonas infections present with diverse clinical manifestations and may show substantial resistance to carbapenems. Early microbiological diagnosis and rational antibiotic selection are essential for optimal management and improved outcomes.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Title of the article: Aeromonas infections in humans: clinical presentation, resistance patterns, and outcomes in a south indian tertiary care centre

  • 期刊论文

  • 发表日期：

    2026年3月9日

查看全文
  • G. Vithiya,
  • M. Jasmine Fathima,
  • M. Srividya,
  • P. Shunmuga Sundaram,
  • T. Rajendran,
  • V. Mangayarkarasi

摘要

Background

Aeromonas species are increasingly recognized as emerging human pathogens capable of causing a wide spectrum of infections ranging from skin and soft tissue infections to life-threatening bacteremia. Data from India describing their clinical spectrum and antimicrobial resistance patterns remain limited.

Methods

We conducted a retrospective study of 61 culture-proven cases of Aeromonas infection identified between 2019 and 2025 at a tertiary care centre in South India. Demographic characteristics, clinical presentation, comorbidities, microbiological findings, antimicrobial susceptibility patterns, treatment, and outcomes were analysed.

Results

The mean patient age was 46 years, and 57% were male. The most common clinical presentations were skin and soft tissue infections (40.9%) and bacteremia (40.9%), while pulmonary and urinary infections were less frequent. Common comorbidities included diabetes mellitus (27.8%) and chronic liver disease (14.7%), and trauma preceded infection in 16.3% of cases. Antimicrobial susceptibility testing showed high resistance to carbapenems, with resistance rates of 54.7% to meropenem and 27.8% to imipenem. In contrast, cephalosporins largely retained activity. Overall, 81.9% of patients recovered, whereas the mortality rate was 13.1%

Conclusion

Aeromonas infections present with diverse clinical manifestations and may show substantial resistance to carbapenems. Early microbiological diagnosis and rational antibiotic selection are essential for optimal management and improved outcomes.