When oral health affects overall health: biofilms, dental infections, and emerging antimicrobial strategies
摘要
Dental health is a crucial component of overall health, yet it is frequently overlooked in discussions about well-being. This article explores the multifaceted aspects of dental infections, primarily focusing on biofilms formed by pathogenic bacteria such as Streptococcus mutans and Porphyromonas gingivalis. These biofilms contribute to dental caries and periodontal disease, conditions that affect oral health and have systemic consequences. Recent advancements in understanding biofilm formation and interactions have led to novel strategies for prevention and treatment, including using nanoparticles and smart hydrogels designed to disrupt biofilm integrity while promoting biocompatibility with human tissues. Furthermore, the article highlights the potential of natural remedies, including herbal extracts, as adjuncts in maintaining oral hygiene and combating microbial infections. A comprehensive overview of biofilm dynamics, including adhesion, maturation, and dispersion, is presented, alongside discussions on innovative therapeutic approaches addressing the limitations of conventional treatments. Ultimately, this article emphasizes the importance of maintaining dental health in preventing a wide spectrum of health issues, reinforcing that the mouth is a gateway to the body.