<p>Urban climate change associated with global climate change and urbanization is a major challenge for most cities worldwide. Implementing climate change mitigation and adaptation is urgent for both developed and developing cities before they suffer locked-in effects. However, addressing urban climate change requires updated and innovative theories, methods, technologies, and strategies for impact assessment, planning and design methods, urban operation and maintenance, and scheme generation. Among them, there are still many challenges and barriers to overcome in which effective communication and exchange among different stakeholders, at different levels, and from different perspectives should be carried out. This special issue, along with the 4th International Conference on Urban Climate and Urban Design, aims to publish outstanding ideas, thoughts, models, techniques, strategies, cases, and practices on the assessment, preparation, mitigation, and adaptation of urban climate change. This special issue has advanced knowledge of climate-related risk assessment, land use and its dynamic impacts, carbon emission estimation and sequestration, urban environmental quality and innovative estimation techniques, climate-adaptive urban planning and design, sustainable and low-carbon building design, and sustainable urban governance. The published outcomes are expected to provide a reference for urban planners, designers, and managers of developing and developed cities to make more scientific decisions to cope with urban climate change.</p>