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Background <p>Vagus nerve stimulation (VNS) is a neuromodulatory therapeutic option for drug-resistant epilepsy.</p> Case Report <p>We present two patients, aged 23 and 29 years, with drug-resistant epilepsy who experienced increased seizures and status epilepticus after application of VNS.</p> Conclusion <p>VNS is generally well tolerated and provides benefits for patients. However, both patients and their families and clinicians should be alert to the rare side effect of triggering seizures.</p>

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A rare side effect of vagal nerve stimulation: increased seizures and status epilepticus

  • 期刊论文

  • 发表日期：

    2026年2月17日

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  • Esra Kochan Kizilkilic,
  • Taner Tanrıverdi,
  • Seher Naz Yeni

摘要

Background

Vagus nerve stimulation (VNS) is a neuromodulatory therapeutic option for drug-resistant epilepsy.

Case Report

We present two patients, aged 23 and 29 years, with drug-resistant epilepsy who experienced increased seizures and status epilepticus after application of VNS.

Conclusion

VNS is generally well tolerated and provides benefits for patients. However, both patients and their families and clinicians should be alert to the rare side effect of triggering seizures.