Scholarlink

Background and aims <p>Little is known about predicting factors for a good outcome (GO) after endovascular treatment (EVT) performed for acute ischemic stroke (AIS) related to large vessel occlusion (LVO) in the over-80s population. We evaluate demographic and procedural predictors of GO from our prospective registry of patients treated during the acute phase of an LVO-related AIS.</p> Methods <p>GO was defined as a 3-month modified Rankin scale (mRS) <InlineEquation ID="IEq1"> <EquationSource Format="TEX">\(\:\le\:\)</EquationSource> </InlineEquation> 3 or equivalent to pre-stroke mRS. Univariate (UVA) and multivariate (MVA) analysis were performed to assess the factors’ independent effect on the outcome. The magnitude of the between-group differences was assessed by calculating the standardized differences (StD). Variables with StD &gt;0,2 were included in the MVA.</p> Results <p>From 182 patients aged ≥ 80, 3-month GO was observed in 31.3% (57/182). The proportion of TICI ≥ 2c-3 was significantly lower in the poor outcome (PO) group compared to the GO group (52% versus 78.9%, StD = 0.591). In univariate logistic regression model, TICI ≥ 2c-3 is associated with a 277% increase in the chances of a GO (OR = 3.77, 95%CI 1.79–7.97, <i>P</i> &lt; 0.001). This association remained significant in multivariate logistic regression model (aOR = 0.77, 95%CI 0.66–0.89, <i>P</i> = 0.000501) even when a hemorrhagic transformation (HT) occurs (p het = 0.57948).</p> Conclusions <p>We show that achieving a TICI score of 2c-3 seems to be the best predictive factor for the outcome in the elderly population. In this group, every effort should be made to achieve excellent recanalization.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Achieving complete recanalization is the best predicting factor of good outcome for thrombectomy in the elderly. Results from a prospective monocentric study

  • 期刊论文

  • 发表日期：

    2025年7月21日

查看全文
  • Manar Abomulay,
  • Philippe Desfontaines,
  • Carla Ciobanu,
  • Denis Brisbois,
  • Olivier Cornet,
  • François Dister,
  • François Delvoye

摘要

Background and aims

Little is known about predicting factors for a good outcome (GO) after endovascular treatment (EVT) performed for acute ischemic stroke (AIS) related to large vessel occlusion (LVO) in the over-80s population. We evaluate demographic and procedural predictors of GO from our prospective registry of patients treated during the acute phase of an LVO-related AIS.

Methods

GO was defined as a 3-month modified Rankin scale (mRS) \(\:\le\:\) 3 or equivalent to pre-stroke mRS. Univariate (UVA) and multivariate (MVA) analysis were performed to assess the factors’ independent effect on the outcome. The magnitude of the between-group differences was assessed by calculating the standardized differences (StD). Variables with StD >0,2 were included in the MVA.

Results

From 182 patients aged ≥ 80, 3-month GO was observed in 31.3% (57/182). The proportion of TICI ≥ 2c-3 was significantly lower in the poor outcome (PO) group compared to the GO group (52% versus 78.9%, StD = 0.591). In univariate logistic regression model, TICI ≥ 2c-3 is associated with a 277% increase in the chances of a GO (OR = 3.77, 95%CI 1.79–7.97, P < 0.001). This association remained significant in multivariate logistic regression model (aOR = 0.77, 95%CI 0.66–0.89, P = 0.000501) even when a hemorrhagic transformation (HT) occurs (p het = 0.57948).

Conclusions

We show that achieving a TICI score of 2c-3 seems to be the best predictive factor for the outcome in the elderly population. In this group, every effort should be made to achieve excellent recanalization.