Scholarlink

<p>This study reports the electropolymerization of 4,4′-methylenedianiline on a glassy carbon electrode (GCE) using cyclic voltammetry. In the subsequent step, a molecularly imprinted polymer was employed to modify the GCE for the indirect detection of acetaminophen (ACT). A potassium hexacyanoferrate (III) (K<sub>3</sub>Fe (CN)<sub>6</sub>) redox probe was utilized to monitor changes in peak current. Under optimized analytical conditions, the ACT concentration exhibited a linear response in the range of 0.5–20&#xa0;mg&#xa0;L⁻<sup>1</sup>, with a detection limit of 0.2&#xa0;mg&#xa0;L⁻<sup>1</sup>. The sensor's performance was successfully validated through the determination of ACT in blood, ampoule, tablets, and milk, confirming its practical applicability.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

An acetaminophen molecularly imprinted electrochemical sensor based a poly 4,4′-methylenedianiline

  • 期刊论文

  • 发表日期：

    2025年8月9日

查看全文
  • Bahareh Hamzeh Khanlou,
  • Mohammad Reza Yaftian,
  • Hassan Shayani-Jam,
  • Farideh Piri

摘要

This study reports the electropolymerization of 4,4′-methylenedianiline on a glassy carbon electrode (GCE) using cyclic voltammetry. In the subsequent step, a molecularly imprinted polymer was employed to modify the GCE for the indirect detection of acetaminophen (ACT). A potassium hexacyanoferrate (III) (K3Fe (CN)6) redox probe was utilized to monitor changes in peak current. Under optimized analytical conditions, the ACT concentration exhibited a linear response in the range of 0.5–20 mg L⁻1, with a detection limit of 0.2 mg L⁻1. The sensor's performance was successfully validated through the determination of ACT in blood, ampoule, tablets, and milk, confirming its practical applicability.