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<p>The cobalt-catalysed approach has been developed for the synthesis of benzoxazoles under aerobic conditions. The easily available substrates, such as 2-aminophenols and aldehydes, studied for the synthesis of benzoxazole products and afforded with good tolerance of functional groups. The synthesised products were obtained in good yields under additive-free and ligand-free reaction conditions.</p> Graphical abstract <p></p>

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An efficient cobalt-catalyzed approach for synthesis of benzoxazoles from 2-aminophenol and aldehydes

  • 期刊论文

  • 发表日期：

    2025年5月3日

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  • Atul S. Pethe,
  • Vikas D. Kadu,
  • Sakshi M. Birajdar,
  • Prajakta B. Patil

摘要

The cobalt-catalysed approach has been developed for the synthesis of benzoxazoles under aerobic conditions. The easily available substrates, such as 2-aminophenols and aldehydes, studied for the synthesis of benzoxazole products and afforded with good tolerance of functional groups. The synthesised products were obtained in good yields under additive-free and ligand-free reaction conditions.

Graphical abstract