Scholarlink

<p>We created a novel family of 5-benzylidene-2-(furan-2-yl)-3-(pyrimidin-2-yl)thiazolidin-4-one (5a-o) to successfully decrease viral diseases linked to antimicrobial resistance (AMR), which is a major public health problem worldwide. Using spectral approaches, the structures of the pertinent chemicals have been identified and confirmed. Compounds with chloro substituents in both the <i>p</i>-position and the <i>m</i>-position showed good activity against the fungi, products with the nitro group at the ring's <i>m</i>-position and methyl, bromo, and nitro substituents in the benzene ring's <i>p</i>-position showed very good activity against bacterial strains. <i>Aspergillus Niger</i> and <i>Fusarium Javanicum</i> In a binary liquid mixture containing 4-thiazolidinone derivatives containing furan and pyrimidine moiety over the whole molality range at temperatures T = (303.15, 308.15, 313.15 and 318.15) K and different solvents DMSO and DMF, density (<i>ρ</i>), ultrasonic velocity (<i>U</i>), and viscosity (<i>η</i>) have been measured.</p> Graphical abstract <p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Synthesis, characterization and biological evaluation, determination of physico chemical parameters at three different temperatures and ADME studies of some 4-thiazolidinone containing furan and pyrimidine moiety

  • 期刊论文

  • 发表日期：

    2025年1月8日

查看全文
  • Umang P. Mehta,
  • Dinesh R. Godhani,
  • Anwar H. Saiyad,
  • Kuldip P. Parmar,
  • Jignasu P. Mehta

摘要

We created a novel family of 5-benzylidene-2-(furan-2-yl)-3-(pyrimidin-2-yl)thiazolidin-4-one (5a-o) to successfully decrease viral diseases linked to antimicrobial resistance (AMR), which is a major public health problem worldwide. Using spectral approaches, the structures of the pertinent chemicals have been identified and confirmed. Compounds with chloro substituents in both the p-position and the m-position showed good activity against the fungi, products with the nitro group at the ring's m-position and methyl, bromo, and nitro substituents in the benzene ring's p-position showed very good activity against bacterial strains. Aspergillus Niger and Fusarium Javanicum In a binary liquid mixture containing 4-thiazolidinone derivatives containing furan and pyrimidine moiety over the whole molality range at temperatures T = (303.15, 308.15, 313.15 and 318.15) K and different solvents DMSO and DMF, density (ρ), ultrasonic velocity (U), and viscosity (η) have been measured.

Graphical abstract