Scholarlink

<p>In this work, sulfur nanoparticles (SNPs) were produced in situ within the calcium alginate (CA) films. The SNP-loaded films were characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM) analysis. As per TEM analysis, most of the particles had oval-shaped geometry with lengths and widths in the range of 152 to 178&#xa0;nm and 41 to 56&#xa0;nm, respectively. The results of water absorption studies in the medium of pH 7.4 revealed that plain sample SNLCA (6)<sub>0</sub> exhibited ‘percent water absorption capacity’ (PWAC) of 247 in 30&#xa0;min, followed by disintegration, while samples SNLCA (6)<sub>1.5</sub> and SNLCA (6)<sub>4.5</sub> showed PWAC of 650 and 735, achieved in 120 and 150&#xa0;min, respectively. The swelling exponent ‘n’ for the samples SNLCA (6)<sub>1.5</sub> and SNLCA (6)<sub>4.5</sub> was 0.45 and 0.89, respectively. The water vapor transmission rate (WVTR) for films SNLCA (6)<sub>0</sub>, SNLCA (6)<sub>1.5,</sub> and SNLCA (6)<sub>4.5</sub> was 4092, 5365, and 5729&#xa0;g/m<sup>2</sup>/day, respectively. The sulfur-loaded samples exhibited a zone of inhibition of 19.5 and 23.0&#xa0;mm, respectively, against Escherichia coli (<i>E. coli</i>). When applied to an artificially created wound in Wistar rats, the nano sulfur-loaded film showed faster healing and re-growth of hair than the plain film.</p> Graphical abstract <p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Sulfur nanoparticles loaded calcium alginate film: synthesis, characterization, and its applications as antimicrobial and wound healing agent

  • 期刊论文

  • 发表日期：

    2026年5月4日

查看全文
  • Ashish Mahere,
  • Jyoti Shrivastava,
  • S. K. Bajpai,
  • Manjula Bajpai

摘要

In this work, sulfur nanoparticles (SNPs) were produced in situ within the calcium alginate (CA) films. The SNP-loaded films were characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM) analysis. As per TEM analysis, most of the particles had oval-shaped geometry with lengths and widths in the range of 152 to 178 nm and 41 to 56 nm, respectively. The results of water absorption studies in the medium of pH 7.4 revealed that plain sample SNLCA (6)0 exhibited ‘percent water absorption capacity’ (PWAC) of 247 in 30 min, followed by disintegration, while samples SNLCA (6)1.5 and SNLCA (6)4.5 showed PWAC of 650 and 735, achieved in 120 and 150 min, respectively. The swelling exponent ‘n’ for the samples SNLCA (6)1.5 and SNLCA (6)4.5 was 0.45 and 0.89, respectively. The water vapor transmission rate (WVTR) for films SNLCA (6)0, SNLCA (6)1.5, and SNLCA (6)4.5 was 4092, 5365, and 5729 g/m2/day, respectively. The sulfur-loaded samples exhibited a zone of inhibition of 19.5 and 23.0 mm, respectively, against Escherichia coli (E. coli). When applied to an artificially created wound in Wistar rats, the nano sulfur-loaded film showed faster healing and re-growth of hair than the plain film.

Graphical abstract